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Enantioselective Iridium-Catalyzed Allylic Alkylation of Racemic Branched Alkyl-Substituted Allylic Acetates with Malonates

Tian-Yuan Zhang, Yi Deng, Kun Wei and Yu-Rong Yang*

*State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China, Email:

T.-Y. Zahng, Y. Deng, K. Wei, Y.-R. Yang, Org. Lett., 2021, 23, 1086-1089.

DOI: 10.1021/acs.orglett.0c04309


Krische's π-allyliridium C,O-benzoate catalyst mediates a regio- and enantioselective allylic substitution of branched alkyl-substituted allylic acetates with malonates.

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ID: J54-Y2021