Ruthenium-Catalyzed Oxidative Cross-Coupling Reaction of Activated Olefins with Vinyl Boronates for the Synthesis of (E,E)-1,3-Dienes
Dattatraya H. Dethe*, Nagabhushana C. Beeralingappa and Amar Uike
*Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India, Email: ddetheiitk.ac.in
D. H. Dethe, N. C. Beeralingappa, A. Uike, J. Org. Chem., 2021, 86, 3444-3455.
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An oxidative cross-coupling reaction between activated olefins and vinyl boronate provides synthetically useful (E,E)-1,3-dienes. Exclusive stereoselectivity (only E,E-isomer) was achieved using base-free, ligand-free, and mild catalytic conditions with [RuCl2(p-cymene)]2 as catalyst.
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