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Visible-Light-Mediated Additive-Free Decarboxylative Ketonization Reaction of Acrylic Acids: An Access to α-Thiocyanate Ketones

Zhi-Lv Wang, Jie Chen, Yan-Hong He* and Zhi Guan*

*Key Laboratory of Applied Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China, Email:,

Z.-L. Wang, J. Chen, Y.-H. He, Z. Guan, J. Org. Chem., 2021, 86, 3741-3749.

DOI: 10.1021/acs.joc.0c02471

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A mild and environmentally friendly visible-light-mediated additive-free decarboxylative functionalization of acrylic acids in the presence of ammonium thiocyanate, the inexpensive organic dye 9,10-dicyanoanthracene as a photocatalyst, and dioxygen as both an oxygen source and an oxidant provides a series of important α-thiocyanate ketones.

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proposed mechanism

Key Words

thiocyanates, oxygen

ID: J42-Y2021