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Amide Iridium Complexes As Catalysts for Transfer Hydrogenation Reduction of N-sulfonylimine

Huiling Wen, Nianhua Luo, Qianheng Zhu and Renshi Luo*

*School of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, China Email:

H. Wen, N. Luo, Q. Zhu, R. Luo, J. Org. Chem., 2021, 86, 3850-3859.

DOI: 10.1021/acs.joc.0c02680

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Water-soluble amide iridium complexes catalyze transfer hydrogenation reduction of N-sulfonylimines under environmentally friendly conditions, affording a series of sulfonamide compounds in excellent yields. This protocol gives an operationally simple, practical, and environmentally friendly strategy for synthesis of sulfonamide compounds.

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Key Words

reduction of imines, formic acid, green chemistry

ID: J42-Y2021