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Transition Metal-Free Oxidative Cross-Coupling Reaction of Activated Olefins with N-Alkyl Amides

Miaomiao Li, Lei Zheng, Li Ma and Yunfeng Chen*

*School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430205, P. R. China, Email:

M. Li, L. Zhang, L. Ma, Y. Chen, J. Org. Chem., 2021, 86, 3989-3998.

DOI: 10.1021/acs.joc.0c02837

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A K2S2O8-mediated transition metal-free oxidative cross-coupling reaction of activated olefins with N-alkyl amides provides N-allylic amides in good yield.

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Key Words

allylamines, potassium peroxydisulfate, γ-lactams

ID: J42-Y2021