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Synthesis of Substituted Benzo[b]thiophenes via Base-Promoted Domino Condensation-Intramolecular C-S Bond Formation

Yogendra Kumar and Hiriyakkanavar Ila*

*New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India, Email:

Y. Kumar, H. Ila, Org. Lett., 2021, 23, 1698-1702.

DOI: 10.1021/acs.orglett.1c00085

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A tandem base-mediated condensation of o-iodoarylacetonitriles/acetates/ketones with (hetero)aryldithioesters and an intramolecular C-S bond formation provides diversely substituted benzothiophenes and heterofused thiophenes in excellent yields.

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Key Words


ID: J54-Y2021