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Coupling Photocatalysis and Substitution Chemistry to Expand and Normalize Redox-Active Halides

Manjula D. Rathnayake and Jimmie D. Weaver III*

*Department of Chemistry, Oklahoma State University, 107 Physical Sciences, Stillwater, Oklahoma 74078, United States, Email: Jimmie.Weaverokstate.edu

M. D. Rathnayake, J. D. Weaver III, Org. Lett., 2021, 23, 2036-2041.

DOI: 10.1021/acs.orglett.1c00173


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Abstract

When used with photocatalysis, bench-stable, commercially available collidinium salts are excellent radical precursors with a broad scope, that can substitute alkyl halides. Furthermore, all of the reaction components are water-soluble, which facilitates product isolation.

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Key Words

benzylation, nitriles, esters, photochemistry


ID: J54-Y2021