Arylation of ortho-Hydroxyarylenaminones by Sulfonium Salts and Arenesulfonyl Chlorides: An Access to Isoflavones
Satenik Mkrtchyan* and Viktor O. Iaroshenko*
*Laboratory of Homogeneous Catalysis and Molecular Design at Center of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, PL-90-363 Łodź, Poland,
Email: sm19860214
gmail.com, viktoricbmm.lodz.pl
S. Mkrtchyan, V. O. Iaroshenko, J. Org. Chem., 2021, 86, 4896-4916.
DOI: 10.1021/acs.joc.0c02294
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Abstract
Arylation of ortho-hydroxyarylenaminones by vast diversities of bench-stable and easy-to-use sulfonium salts and arenesulfonyl chlorides enables a straightforward synthesis of 3-arylchromones in very good yields. Light-mediated photoredox as well as electrophilic arylation showed good efficiency.
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proposed mechanism for electrophilic arylation
Visible-light-mediated arylation of ortho-hydroxyarylenaminones: direct access to isoflavones
S. Mkrtchyan, V. O. Iaroshenko, Chem. Commun., 2020, 57, 2606-2609.
Key Words
Isoflavones, Photochemistry
ID: J42-Y2021
