Palladium-Catalyzed Linear Hydrothiocarbonylation of Unactivated Terminal Alkenes: Synthesis of Aliphatic Thioesters
Wangzhi Yu, Jian Han, Dongmei Fang, Min Wang and Jian Liao*
*Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, P.R. China,
Email: jliao
cib.ac.cn
W. Yu, J. Han, D. Fang, M. Wang, J. Liao, Org. Lett., 2021, 23, 2482-2487.
DOI: 10.1021/acs.orglett.1c00406
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Abstract
A Pd-catalyzed hydrothiocarbonylation of unactivated terminal alkenes provides aliphatic thioesters with exclusive linear selectivity under mild reaction conditions in very good yields, broad substrate scope, and broad functional group tolerance.
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Key Words
carboxylations, thiolation, multicomponent reactions
ID: J54-Y2021
