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Sodium Aminodiboranate, a New Reagent for Chemoselective Reduction of Aldehydes and Ketones to Alcohols

Jin Wang, Yu Guo, Shouhu Li, Xuenian Chen*

*School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. of China, Email: xnchenhtu.edu.cn

J. Wang, Y. Guo, S. Li, X. Chen, Synlett, 2021, 32, 1104-1108.

DOI: 10.1055/s-0040-1705944 (free Supporting Information)


Abstract

Sodium aminodiboranate (NaNH2(BH3)2, NaADBH) is a member of the borane family with superior performance in chemoselective reduction. NaADBH can rapidly reduce aldehydes and ketones to the corresponding alcohols in high efficiency and selectivity under mild conditions. Steric and electronic effects have only a limited influence.

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Hydroboration Reaction and Mechanism of Carboxylic Acids using NaNH2(BH3)2, a Hydroboration Reagent with Reducing Capability between NaBH4 and LiAlH4

J. Wang, M.-Y. Ju, X. Wang, Y.-N. Ma, D. Wei, X. Chen, J. Org. Chem., 2021, 86, 5305-5316.


Key Words

sodium aminodiboranate, hydrogenation, reduction of carbonyl compounds


ID: J72-Y2021