Regioselective Three-Component Synthesis of Vicinal Diamines via 1,2-Diamination of Styrenes
Jie Cao, Daqi Lv, Fei Yu, Mong-Feng Chiou, Yajun Li and Hongli Bao*
*Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, 155 Yangqiao Road West, Fuzhou, Fujian 350002, P. R. China,
Email: hlbao
fjirsm.ac.cn
J. Cao, D. Lv, F. Yu, M.-F. Chiou, Y. Li, H. Bao, Org. Lett., 2021, 23, 3184-3189.
DOI: 10.1021/acs.orglett.1c00898
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Abstract
A regioselective intermolecular three-component reaction of styrenes with acetonitrile and azodicarboxylates provides vicinal diamination products in good yields via the Ritter reaction.
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proposed mechanism
Key Words
diamines, hydrazines, Ritter Reaction, multicomponent reactions
ID: J54-Y2021
