Nickel-Catalyzed Intramolecular Nucleophilic Addition of Aryl Halides to Aryl Ketones for the Synthesis of Benzofuran Derivatives
Xiao-Rui Zhu, Chen-Liang Deng*
*College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. of China,
Email: dcl78
wzu.edu.cn
X.-R. Zhu, C.-L. Deng, Synthesis, 2021, 53, 1842-1848.
DOI: 10.1055/s-0040-1706662
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Abstract
A nickel-catalyzed intramolecular nucleophilic addition reaction of aryl halides to aryl ketones provides benzofuran derivatives in moderate yields. A number of substrates bearing electron-donating or electron-withdrawing groups can be converted.
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Key Words
nickel, zinc powder, intramolecular addition, cyclization, benzofurans
ID: J66-Y2021
