Milled Dry Ice as a C1 Source for the Carboxylation of Aryl Halides

Connor J. O'Brien, David A. Nicewicz*

*Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA, Email: nicewiczunc.edu

C. J. O'Brien, D. A. Nicewicz, Synlett, 2021, 32, 814-816.

DOI: 10.1055/a-1384-0159

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Abstract

The use of milled dry ice permitts a practical synthesis of arylcarboxylic acids with increased yields compared to those obtained with gaseous CO₂, as previously reported in the literature.

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Key Words

carboxylation, carbon dioxide, C1 source, dry ice, arylcarboxylic acids

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ID: J72-Y2021