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Mild Copper-Catalyzed Addition of Arylboronic Esters to Di-tert-butyl Dicarbonate: An Easy Access to Methyl Arylcarboxylates

Jin-Di Xu, Xiao-Bo Su, Cai Wang, Li-Wei Yao, Jing-Hui Liu*, Guo-Qin Hu*

*School of Chemical Engineering, Zhengzhou University, Zhengzhou, Henan 450001, P. R. of China, Email:,

J.-D. Xu, X.-B. Su, C. Wang, L.-W. Yao, J.-H. Liu, G.-Q. Hu, Synlett, 2021, 32, 833-837.

DOI: 10.1055/a-1377-7369 (free Supporting Information)

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An efficient copper-catalyzed addition of arylboronic esters to (Boc)2O provides methyl arylcarboxylates under exceedingly mild conditions. The reaction is compatible with a variety of synthetically relevant functional groups.

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Key Words

copper catalysis, arylboronic esters, addition, carboxylation, methyl arylcarboxylates

ID: J72-Y2021