Ni-Catalyzed Reductive Allylation of α-Chloroboronates to Access Homoallylic Boronates
Yixian Lou, Jian Qiu, Kai Yang, Feng Zhang, Chenglan Wang and Qiuling Song*
*Institute of Next Generation Matter Transformation, College of Materials Science Engineering at Huaqiao University, Xiamen, Fujian 361021, China,
Email: qsong
hqu.edu.cn
Y. Lou, J. Qiu, K. Yang, F. Zhang, C. Wang, Q. Song, Org. Lett., 2021, 23, 4564-4569.
DOI: 10.1021/acs.orglett.1c01213
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Abstract
A Ni-catalyzed reductive allylation of α-chloroboronates with allyl sulfones efficiently provides the corresponding homoallylic boronates, which could be readily converted into valuable homoallylic alcohols or amines or 1,4-diboronates. This reaction features a broad substrate scope with good functional group compatibility.
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proposed mechanisms
Key Words
ID: J54-Y2021
