Room-Temperature Amination of Chloroheteroarenes in Water by a Recyclable Copper(II)-Phosphaadamantanium Sulfonate System
Udaysinh Parmar, Dipesh Somvanshi, Santosh Kori, Aman A. Desai, Rambabu Dandela, Dilip K. Maity and Anant R. Kapdi*
*Department of Chemistry, Institute of Chemical Technology, Nathalal Parekh Road, Matunga, Mumbai 400019, India,
Email: ar.kapdi
ictmumbai.edu.in
U. Parmar, D. Somvanshi, S. Kori, A. A. Desai, R. Dandela, D. K. Maity, A. R. Kapdi, J. Org. Chem., 2021, 86, 8900-8925.
see article for more reactions
Abstract
An efficient copper-based catalytic system (Cu/PTABS) enables an amination of a chloroheteroarenes at ambient temperature in water as the sole reaction solvent. A wide variety of chloroheteroarenes could be coupled efficiently with primary and secondary amines as well as selected amino acid esters under mild reaction conditions.
see article for more examples
Catalytic Amination of Purine and Purine Riboside with Secondary Amines - see article for more examples
Pd/PTABS: Catalyst for Room Temperature Amination of Heteroarenes
S. S. M. Bandaru, S. Bhilare, N. Chrysochos, V. Gayakhe, I. Trentin, C. Schulzke, A. R. Kapdi, Org. Lett., 2018, 20, 473-476.
Key Words
benzoxazoles, benzothiazoles, Ullmann coupling
ID: J42-Y2021
