Synthetic Route to Enaminones via Metal-Free Four-Component Sequential Reactions of Aryl Olefins with CHCl3, Et3N, and TBHP
Jiantao Zhang, Peng Zhou, Aiguo Yin*, Shuhua Zhang and Weibing Liu*
*Guangdong University of Petrochemical Technology, Guandu Road, Maoming 525000, P. R. China, Email: yinlife8hotmail.com, lwb409gdupt.edu.cn
J. Zhang, P. Zhou, A. Yin, S. Zhang, W. Liu, J. Org. Chem., 2021, 86, 8980-8986.
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An efficient and modular strategy based on a four-component sequential reaction provides enaminones under mild conditions without a catalyst in one pot. Furthermore, the products could be transformed into thiadiazoles.
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