Palladium-Catalyzed C-P(III) Bond Formation by Coupling ArBr/ArOTf with Acylphosphines
Xingyu Chen, Hongyu Wu, Rongrong Yu, Hong Zhu* and Zhiqian Wang*
*Department of Organic Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, China, Email: zhuho128126.com, wangzhqmail.buct.edu.cn
X. Chen, H. Wu, R. Yu, H. Zhu, Z. Wang, J. Org. Chem., 2021, 86, 8987-8996.
DOI: 10.1021/acs.joc.1c00937
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Abstract
Acylphosphines are inert to air and moisture. A palladium-catalyzed C-P bond formation reaction using acylphosphines as phosphination reagents shows practicable reactivity with ArBr and ArOTf to afford trivalent phosphines directly in good yields with a broad substrate scope and functional group tolerance.
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proposed mechanism
Key Words
ID: J42-Y2021