Iridium-Catalyzed Enantioconvergent Allylation of a Boron-Stabilized Organozinc Reagent

Panchi Guo and Miao Zhan*

*Institute of Medical Research, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, P. R.China, Email: mzhannwpu.edu.cn

P. Guo, M. Zhan, J. Org. Chem., 2021, 86, 9905-9913.

DOI: 10.1021/acs.joc.1c01076

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Abstract

An iridium-catalyzed enantioconvergent coupling of the versatile boron-stabilized organozinc reagent BpinCH₂ZnI with racemic branched allylic carbonates provides various chiral homoallylic organoboronic esters in good yields with excellent enantioselectivities. The homoallylboronates can easily be converted to other useful families of compounds.

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Key Words

alkylboronates, allylation

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ID: J42-Y2021