Radical Anion Promoted Chemoselective Cleavage of Csp2-S Bond Enables Formal Cross-Coupling of Aryl Methyl Sulfones with Alcohols
Jixiang Bai, Tianxin Wang, Botao Dai, Qingchao Liu*, Peiyuan Yu* and Tiezheng Jia*
*Northwest University, Taibai North Road 229, Xi'an, Shanxi 710069; SUSTech, 1088 Xueyuan Boulevard, Shenzhen, Guangdong 518055, P.R. China, Email: liuqc21nwu.edu.cn, yupysustech.edu.cn, jiatzsustech.edu.cn
J. Bai, T. Wang, B. Dai, Q. Liu, P. Yu, T. Jia, Org. Lett., 2021, 23, 5761-5765.
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A formal cross-coupling of aryl methyl sulfones and alcohols affords alkyl aryl ethers via an SRN1 pathway. A dimsyl-anion initiated radical chain process was revealed as the major pathway.
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