Light-Promoted and Tertiary-Amine-Assisted Hydroxysulfenylation of Alkenes: Selective and Direct One-Pot Synthesis of β-Hydroxysulfides
Jing Shi, Xue-Wang Gao, Qing-Xiao Tong and Jian-Ji Zhong*
*Department of Chemistry, Shantou University, Shantou, Guangdong 515063, P. R. China, Email: jjzhongstu.edu.cn
J. Shi, X.-W. Gao, Q.-X. Tong, J.-J. Zhong, J. Org. Chem., 2021, 86, 12922-12931.
see article for more reactions
A visible light-promoted and tertiary-amine-assisted hydroxysulfenylation of both electron-rich and electron-deficient alkenes with thiophenols provides β-hydroxysulfides in very good yields. This simple and sustainable approach features mild reaction conditions, high efficiency, and excellent functional group tolerance.
see article for more examples
aryl sulfides, benzylic alcohols, oxygen, photochemistry