Nickel-Catalyzed α-1,3-Dienylation of 1,3-Dicarbonyl Compounds with Propargylic Carbonates

Naoki Ishida*, Yuka Kamino, Masahiro Murakami*

*Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan, Email: naisidasbchem.kyoto-u.ac.jp, murakamisbchem.kyoto-u.ac.jp

N. Ishida, Y. Kamino, M. Murakami, Synlett, 2021, 32, 1621-1624.

DOI: 10.1055/a-1282-9731

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Abstract

A nickel-catalyzed reaction of 1,3-dicarbonyl compounds with α-methyl-substituted propargylic carbonate incorporates a 1,3-dienyl unit at the α-position of the 1,3-dicarbonyl compound.

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Key Words

α-1,3-dienylation, active methylene compounds

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ID: J72-Y2021