Asymmetric [3 + 1]-Cycloaddition Reaction via Diazo Discrimination
Yong Xu, Zhen Wang and Jiangtao Sun*
*Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, P. R. China,
Email: jtsun
cczu.edu.cn
Y. Xu, Z. Wang, J. Sun, Org. Lett., 2021, 23, 7613-7617.
DOI: 10.1021/acs.orglett.1c02825
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Abstract
Chiral bisoxazoline copper(I) complexes catalyze an enantioselective [3 + 1]-cycloaddition of two structurally different diazo compounds to provide cyclobutenes containing a quaternary stereocenter.
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proposed mechanism
Key Words
ID: J54-Y2021
