Nickel-Catalyzed Ligand-Free Hiyama Coupling of Aryl Bromides and Vinyltrimethoxysilane

Shichao Wei, Yongjun Mao*, Shi-Liang Shi*

*Shanghai University of Engineering Science, Shanghai 201620, SIOC, CAS, 345 Lingling Road, Shanghai 200032, P. R. of China Email: yongjun.maohotmail.com, shiliangshisioc.ac.cn

S. Wei, Y. Mao, S.-L. Shi, Synlett, 2021, 32, 1670-1674.

DOI: 10.1055/a-1379-1584

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Abstract

A Ni-catalyzed Hiyama coupling of aryl halides with cheap, nontoxic, and stable vinyltrimethoxysilane as the vinyl donor proceeds under mild and ligand-free conditions. The method provides a diverse variety of styrene derivatives in high yields with excellent functional group compatibility.

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Key Words

nickel catalysis, vinylation, cross-coupling, Hiyama coupling, ligand-free conditions, vinylsilane, aryl halide

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ID: J72-Y2021