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Lewis Base Catalyzed Dioxygenation of Olefins with Hypervalent Iodine Reagents

Liangkun Pan, Zhihai Ke* and Ying-Yeung Yeung*

*Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, Email:,

L. Pan, Z. Ke, Y.-Y. Yeung, Org. Lett., 2021, 23, 8174-8178.

DOI: 10.1021/acs.orglett.1c02872

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Lewis bases catalyze vicinal dioxygenation of olefins with hypervalent iodine reagents under mild conditions. The reaction tolerates various functional groups.

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proposed mechanism

Key Words

1,2-diols, PIFA, organocatalysis

ID: J54-Y2021