Organic Chemistry Portal

Abstracts

Search:

Lewis Base Catalyzed Dioxygenation of Olefins with Hypervalent Iodine Reagents

Liangkun Pan, Zhihai Ke* and Ying-Yeung Yeung*

*Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, Email: chmkzcuhk.edu.hk, yyyeungcuhk.edu.hk

L. Pan, Z. Ke, Y.-Y. Yeung, Org. Lett., 2021, 23, 8174-8178.

DOI: 10.1021/acs.orglett.1c02872 (free Supporting Information)


see article for more reactions

Abstract

Lewis bases catalyze vicinal dioxygenation of olefins with hypervalent iodine reagents under mild conditions. The reaction tolerates various functional groups.

see article for more examples

proposed mechanism



Key Words

1,2-diols, PIFA, organocatalysis


ID: J54-Y2021