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Indium(III)-Catalyzed Synthesis of Primary Carbamates and N-Substituted Ureas

Isha Jain, Payal Malik*

*Department of Chemistry, Sant Longowal Institute of Engineering and Technology, Longowal, Punjab, 148106, India, Email:

I. Jain, P. Malik, Synthesis, 2022, 54, 93-97.

DOI: 10.1055/s-0040-1720927


Indium triflate catalyzes a synthesis of primary carbamates from alcohols and urea as an ecofriendly carbonyl source. Various linear, branched, and cyclic alcohols were converted into the corresponding carbamates in good to excellent yields. This method also provided access to N-substituted ureas by carbamoylation of amines. All the products were obtained by simple filtration or crystallization.

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Key Words

carbamates, alcohols, ureas, indium catalysis, nucleophilic substitution

ID: J66-Y2022