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A Convenient Procedure for Sonogashira Reactions Using Propyne

Joshua L. Alterman, George A. Kraus*

*Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA, Email: gakrausiastate.edu

J. L. Alterman, G. A. Kraus, Synthesis, 2022, 54, 655-657.

DOI: 10.1055/a-1648-7074


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Abstract

A modified Sonogashira coupling of aryl iodides and only two equivalents of a commercially available propyne in THF solution was achieved at low temperatures.

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Key Words

Sonogashira coupling, propyne, ozonolysis, benzofuranone


ID: J66-Y2022