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Photo-Thermo-Mechanochemical Approach to Synthesize Quinolines via Addition/Cyclization of Sulfoxonium Ylides with 2-Vinylanilines Catalyzed by Iron(II) Phthalocyanine

Luyao Liu, Jingyang Lin, Mingxuan Pang, Huile Jin, Xiaochun Yu* and Shun Wang*

*College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China, Email:,

L. Liu, J. Lin, M. Pang, H. Jin, X. Yu, S. Wang, Org. Lett., 2022, 24, 1146-1151.

DOI: 10.1021/acs.orglett.1c04220

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Iron(II) phthalocyanine catalyzes a photo-thermo-mechanochemical synthesis of quinolines. This solvent-free transformation features a cost-efficient catalytic system and operational simplicity, and shows good substrate tolerance, providing a green alternative to existing thermal approaches.

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proposed mechanism

Key Words

quinolines, photochemistry, mechanochemistry, green chemistry

ID: J54-Y2022