Room Temperature Cu-Catalyzed N-Arylation of Oxazolidinones and Amides with (Hetero)Aryl Iodides
Subhajit Bhunia, Subhadip De and Dawei Ma*
*Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China,
Email: madw
sioc.ac.cn
S. Bhunia, S. De, D. Ma, Org. Lett., 2022, 24, 1253-1257.
DOI: 10.1021/acs.orglett.2c00122
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Abstract
N,N'-Bis(pyridin-2-ylmethyl)oxalamide (BPMO) is an efficient ligand for the Cu-catalyzed N-arylation of oxazolidinones and amides with (hetero)aryl iodides at room temperature. The reactions offer excellent chemoselectivity between aryl iodides and aryl bromides and tolerate a wide range of functional groups.
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Key Words
ID: J54-Y2022
