Copper-Catalyzed Regiodivergent and Enantioselective Hydrosilylation of Allenes

Jian-Lin Xu, Zhe-Yuan Xu, Zi-Lu Wang, Wei-Wei Ma, Xin-Yue Sun, Yao Fu* and Yun-He Xu*

*Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. China, Email: fuyaoustc.edu.cn, xyh0709ustc.edu.cn

J.-L. Xu, Z.-Y. Xu, Z.-L. Wang, W.-W. Ma, X.-Y. Sun, Y. Fu, Y.-H. Xu, J. Am. Chem. Soc., 2022, 144, 5535-5542.

DOI: 10.1021/jacs.2c00260

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Abstract

A copper-catalyzed regiodivergent hydrosilylation of a wide range of simple allenes provides linear and branched allylsilanes depending on the choice of solvents. Furthermore, branched allylsilanes were obtained with high enantioselectivity in the presence of a C2-symmetric bisphosphine ligand.

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CyXantphos, (R)-3,5-tBu-MeOBiPHEP

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Key Words

allylsilanes

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ID: J48-Y2022