Organic Chemistry Portal

Abstracts

Search:

Palladium-Catalyzed Reductive Aminocarbonylation of o-Iodophenol-Derived Allyl Ethers with o-Nitrobenzaldehydes to 3-Alkenylquinolin-2(1H)-ones

Jian-Li Liu, Wei Wang, Xinxin Qi* and Xiao-Feng Wu*

*Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, China; Leibniz-Institut für Katalyse e.V., Rostock 18059, Germany, Email: xinxinqizstu.edu.cn, xiao-feng.wucatalysis.de

J.-L. Liu, W. Wang, X. Qi, X.-F. Wu, Org. Lett., 2022, 24, 2248-2252.

DOI: 10.1021/acs.orglett.2c00648


see article for more reactions

Abstract

An attractive palladium-catalyzed reductive aminocarbonylation reaction of o-iodophenol-derived allyl ethers with o-nitrobenzaldehydes provides 3-alkenylquinolin-2(1H)-one derivatives in very good yields in the presence of Mo(CO)6 as both CO surrogate and reductant.

see article for more examples

proposed mechanism



Key Words

2-quinolones


ID: J54-Y2022