Palladium-Catalyzed Reductive Aminocarbonylation of o-Iodophenol-Derived Allyl Ethers with o-Nitrobenzaldehydes to 3-Alkenylquinolin-2(1H)-ones
Jian-Li Liu, Wei Wang, Xinxin Qi* and Xiao-Feng Wu*
*Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, China; Leibniz-Institut für Katalyse e.V., Rostock 18059, Germany, Email: xinxinqizstu.edu.cn, xiao-feng.wucatalysis.de
J.-L. Liu, W. Wang, X. Qi, X.-F. Wu, Org. Lett., 2022, 24, 2248-2252.
DOI: 10.1021/acs.orglett.2c00648
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Abstract
An attractive palladium-catalyzed reductive aminocarbonylation reaction of o-iodophenol-derived allyl ethers with o-nitrobenzaldehydes provides 3-alkenylquinolin-2(1H)-one derivatives in very good yields in the presence of Mo(CO)6 as both CO surrogate and reductant.
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proposed mechanism
Key Words
ID: J54-Y2022