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Alkyne Metathesis with d2 Re(V) Alkylidyne Complexes Supported by Phosphino-Phenolates: Ligand Effect on Catalytic Activity and Applications in Ring-Closing Alkyne Metathesis

Mingxu Cui, Herman H. Y. Sung, Ian D. Williams* and Guochen Jia*

*Department of Chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, SAR 000000, China, Email:,

M. Cui, H. H. Y. Sung, I. D. Williams, G. Jia, J. Am. Chem. Soc., 2022, 144, 6349-6360.

DOI: 10.1021/jacs.2c00368

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d2 Re(V) alkylidyne complexes bearing two decorated phosphino-phenolates (POs) and a labile pyridine ligand can efficiently promote homometathesis as well as ring-closing alkyne metathesis (RCAM) of methyl-capped diynes. A wide range of functional groups including ethers, esters, ketones, aldehydes, alcohols, phenols, amines, amides, and heterocycles are tolerated.

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proposed mechanism

Key Words

alkynes, macrolactones

ID: J48-Y2022