Alkyne Metathesis with d² Re(V) Alkylidyne Complexes Supported by Phosphino-Phenolates: Ligand Effect on Catalytic Activity and Applications in Ring-Closing Alkyne Metathesis

Mingxu Cui, Herman H. Y. Sung, Ian D. Williams* and Guochen Jia*

*Department of Chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong, SAR 000000, China, Email: chwillust.hk, chjiagust.hk

M. Cui, H. H. Y. Sung, I. D. Williams, G. Jia, J. Am. Chem. Soc., 2022, 144, 6349-6360.

DOI: 10.1021/jacs.2c00368

---

see article for more reactions

Abstract

d² Re(V) alkylidyne complexes bearing two decorated phosphino-phenolates (POs) and a labile pyridine ligand can efficiently promote homometathesis as well as ring-closing alkyne metathesis (RCAM) of methyl-capped diynes. A wide range of functional groups including ethers, esters, ketones, aldehydes, alcohols, phenols, amines, amides, and heterocycles are tolerated.

see article for more examples

proposed mechanism

---

---

Key Words

alkynes, macrolactones

---

ID: J48-Y2022