Synthesis of Allenyl-Bdan via Cu(I)-Catalyzed Borylation of Propargyl gem-Dichlorides
Ke-Fan Wu, Dong-Ting Dai, Xin-Yue Sun and Yun-He Xu*
*Department of Chemistry, University of Science and Technology of China, Hefei 230026, China,
Email: xyh0709
ustc.edu.cn
K.-F. Wu, D.-T. Dai, X.-Y. Sun, Y.-H. Xu, Org. Lett., 2022, 24, 2660-2664.
DOI: 10.1021/acs.orglett.2c00704
see article for more reactions
Abstract
A copper-catalyzed borylation of propargyl dichlorides provides chloro-substituted allenyl-Bdan products in very good yields under mild reaction conditions. Derivatizations of the allenyl-Bdan products are also demontrated.
see article for more examples
proposed mechanism
pinB-Bdan
Key Words
allenes, allenylboronic acid derivatives
ID: J54-Y2022
