Azolium Aurates as Pre-Catalysts for the Oxidative Coupling of Terminal Alkynes under Mild Conditions

Xinyuan Ma, Nikolaos V. Tzouras, Min Peng, Kristof Van Hecke and Steven P. Nolan*

*Department of Chemistry and Centre for Sustainable Chemistry, Ghent University, Krijgslaan 281, S-3, 9000 Ghent, Belgium, Email: steven.nolanugent.be

X. Ma, N. V. Tzouras, M. Peng, K. Van Hecke, S. P. Nolan, J. Org. Chem., 2022, 87, 4883-4893.

DOI: 10.1021/acs.joc.2c00237

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Abstract

Low loadings of imidazol(in)ium aurates catalyze a simple and efficient oxidative coupling of terminal alkynes. This approach displays high functional group tolerance and leads to a broad range of 1,3-diyne compounds in good yields in air under mild and sustainable conditions.

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Key Words

1,3-Diynes, Phenyliodonium Diacetate

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ID: J42-Y2022