Cobalt(III)-Catalyzed Regio- and Chemoselective [4 + 2]-Annulation of N-Chlorobenzamides/Acrylamides with 1,3-Dienes at Room Temperature
Balu Ramesh and Masilamani Jeganmohan*
*Department of Chemistry, Indian Institute of Technology
Madras, Chennai, Tamil Nadu 600036, India, Email: mjeganmohan
iitm.ac.in
B. Ramesh, M. Jeganmohan, J. Org. Chem., 2022, 87, 6902-6909.
DOI: 10.1021/acs.joc.2c00072
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Abstract
Co(III)-catalyzed regio- and chemoselective redox-neutral C-H annulation of arylamides/acrylamides with 1,3-dienes provides 3,4-dihydroisoquinolinones in good yields. Furthermore, the prepared 3,4-dihydroisoquinolinones can be converted into useful oxirane derivatives in good yields.
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proposed mechanism
Key Words
ID: J42-Y2022
