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Copper-Catalyzed Markovnikov Selective 3,4-Hydrosilylation of 2-Substituted 1,3-Dienes

Ying Wang, Zi-Lu Wang, Wei-Wei Ma and Yun-He Xu*

*Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. China, Email:

Y. Wang, Z.-L. Wang, W.-W. Ma, Y.-H. Xu, Org. Lett., 2022, 24, 4081-4086.

DOI: 10.1021/acs.orglett.2c01558

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The use of a bisphosphine ligand with a rigid backbone enables a copper-catalyzed regioselective Markovnikov 3,4-hydrosilylation of 2-substituted 1,3-dienes in better yield and selectivity.

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proposed mechanism

Synthesis of Structurally Diverse Allylsilanes via Copper-Catalyzed Regiodivergent Hydrosilylation of 1,3-Dienes

Z.-L. Wang, Y. Wang, J.-L. Xu, M. Zhao, K.-Y. Dai, C.-C. Shan, Y.-H. Xu, Org. Lett., 2021, 23, 4736-4742.

Key Words


ID: J54-Y2022