Copper-Catalyzed Markovnikov Selective 3,4-Hydrosilylation of 2-Substituted 1,3-Dienes
Ying Wang, Zi-Lu Wang, Wei-Wei Ma and Yun-He Xu*
*Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. China,
Email: xyh0709
ustc.edu.cn
Y. Wang, Z.-L. Wang, W.-W. Ma, Y.-H. Xu, Org. Lett., 2022, 24, 4081-4086.
DOI: 10.1021/acs.orglett.2c01558
see article for more reactions
Abstract
The use of a bisphosphine ligand with a rigid backbone enables a copper-catalyzed regioselective Markovnikov 3,4-hydrosilylation of 2-substituted 1,3-dienes in better yield and selectivity.
see article for more examples
proposed mechanism
Z.-L. Wang, Y. Wang, J.-L. Xu, M. Zhao, K.-Y. Dai, C.-C. Shan, Y.-H. Xu, Org. Lett., 2021, 23, 4736-4742.
Key Words
ID: J54-Y2022
