Organic Chemistry Portal



Blue LED-Promoted Syntheses of Phosphorothioates and Phosphorodithioates

Bo-Ru Shen, Pratheepkumar Annamalai, Shih-Fang Wang, Rekha Bai and Chin-Fa Lee*

*Department of Chemistry, National Chung Hsing University, Taichung City, Taiwan 402, R.O.C., Email:

B.-R. Shen, P. Annamalai, S.-F. Wang, R. Bai, C.-F. Lee, J. Org. Chem., 2022, 87, 8858-8870.

DOI: 10.1021/acs.joc.2c00323

see article for more reactions


Blue LED irradition promotes an environmentally friendly synthesis of phosphorochalcogenoates, phosphorochalcogenothioates, and phosphinothioates in very good yields under under metal-free, ligand-free, oxidant-free, and photocatalyst-free conditions with minimum chemical waste generation and high atom economy.

see article for more examples

Key Words

Phosphorothioates, Phosphorodithioates

ID: J42-Y2022