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Selective Reduction of Quinolinones Promoted by a SmI2/H2O/MeOH System

Dengbing Xie and Songlin Zhang*

*College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou 215123, China, Email: zhangslsuda.edu.cn

D. Xie, S. Zhang, J. Org. Chem., 2022, 87, 8757-8763.

DOI: 10.1021/acs.joc.2c00389

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Abstract

The combination of SmI2/H2O/MeOH promotes a selective reduction of quinolin-2(1H)-ones to afford 3,4-dihydroquinoline-2(1H)-ones under mild conditions with good to excellent yields.

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Key Words

3,4-dihydroquinoline-2(1H)-ones, samarium diiodide

ID: J42-Y2022