(NH4)2S2O8-Mediated Metal-Free Decarboxylative Formylation/Acylation of α-Oxo/Ketoacids and Its Application to the Synthesis of Indole Alkaloids
Votarikari Dinesh and Rajagopal Nagarajan*
*School of Chemistry, University of Hyderabad, Hyderabad 500046, Telangana, India, Email: nagarajanuohyd.ac.in
V. Dinesh, R. Nagarajan, J. Org. Chem., 2022, 87, 10359-10365.
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A direct decarboxylative cross-coupling of α-oxo/ketoacids with indoles and β-carbolines in the presence of (NH4)2S2O8 enables a metal-free formylation/acylation in moderate to good yields under mild reaction conditions.
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