Electrochemical Reduction of Aldehydes and Ketones for the Synthesis of Alcohols and Diols under Ambient Conditions
Lei Wang, Xiao Zhang, Raymond Yang Xia, Chao Yang*, Lin Guo*, Wujiong Xia
*State Key Lab of Urban Water Resource and Environment, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, P. R. of China, Email: xyyanghit.edu.cn, guolinhit.edu.cn
L. Wang, X. Zhang, R. Y. Xia, C. Yang, L. Guo, W. Xia, Synlett, 2022, 33, 1302-1308.
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An electrochemical reduction of carbonyl compounds, including ketones and aldehydes provides a variety of alcohols or diols as major products with decent yields. This sustainable and practical reaction proceeds smoothly in air at ambient temperatures with DABCO as the sacrificial reductant. The direct electrochemical reduction is either followed by protonation or radical-radical homocoupling.
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electrochemistry, reduction, transition-metal-free, alcohols, pinacols, carbonyl compounds