Iridium-Catalyzed Branch-Selective and Enantioselective Hydroalkenylation of α-Olefins through C-H Cleavage of Enamides
Xin Sun, En-Ze Lin and Bi-Jie Li*
*Center of Basic Molecular Science (CBMS), Department of Chemistry, Tsinghua University, Beijing 100084, China, Email: bijielimail.tsinghua.edu.cn
X. Sun, E.-Z. Lin, B.-J. Li, J. Am. Chem. Soc., 2022, 144, 17351-17358.
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An atom-economical iridium-catalyzed asymmetric hydroalkenylation of α-olefins through directed C-H cleavage of enamides is highly branch-selective and enantioselective, delivering trisubstituted alkenes with an allylic stereocenter.
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