Electromagnetic Mill Promoted Mechanochemical Solvent-Free Palladium-Catalyzed Borylation of Aryl Bromides
Yunxia Liu, Xin Li, Qing Liu, Xinjin Li and Hui Liu*
*School of Chemistry and Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, People’s Republic of China, Email: huiliu1030163.com
Y. Liu, X. Li, Q. Liu, X. Li, H. Liu, Org. Lett., 2022, 24, 6604-6608.
DOI: 10.1021/acs.orglett.2c02600
Abstract
An electromagnetic mill (EMM) can be used for a mechanochemical solvent-free palladium-catalyzed borylation of aryl bromides using low palladium catalyst loading. This protocol offers broad substrate scope, good functional group tolerance, short reaction times, no additional heating, and practical gram-scale synthesis.
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Key Words
Miyaura Borylation, Mechanochemistry
ID: J54-Y2022