Synthesis of Ynones via N-Iodosuccinimide-Mediated Oxidation of Propargyl Alcohols under Mild Conditions
Hongbo Qi, Shuai Xu, Ruiguo Zhao* and Shufeng Chen*
*Department of Chemistry and Chemical Engineering, Inner
Mongolia University, Hohhot 010021, China, Email: zhaoruig
imu.edu.cn,
shufengchenimu.edu.cn
H. Qi, S. Xu, R. Zhao, S. Chen, J. Org. Chem., 2022, 87, 13726-13733.
DOI: 10.1021/acs.joc.2c01386
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Abstract
N-Iodosuccinimide (NIS) mediates a convenient and mild oxidation of propargyl alcohols for the construction of ynones in good yields.
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proposed mechanism
Key Words
ID: J42-Y2022
