Photoelectrochemical Asymmetric Catalysis Enables Direct and Enantioselective Decarboxylative Cyanation
Xiao-Li Lai, Ming Chen, Yuqi Wang, Jinshuai Song* and Hai-Chao Xu*
*Zhengzhou University, Zhengzhou, Henan 450001; Xiamen University, Xiamen 361005, PR China,
Email: jssong
zzu.edu.cn, haichao.xuxmu.edu.cn
X.-L. Lai, M. Chen, Y. Wang, J. Song, H.-C. Xu, J. Am. Chem. Soc., 2022, 144, 20201-20206.
DOI: 10.1021/jacs.2c09050
Abstract
A photoelectrochemical reaction converts carboxylic acids to enantioenriched nitriles by employing cerium/copper relay catalysis with a cerium salt for catalytic decarboxylation and a chiral copper complex for stereoselective C-CN formation.
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proposed mechanism
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Key Words
nitriles, electrochemistry, photochemistry
ID: J48-Y2022
