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Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones

Sumit K. Singh, Sunil Kumar, Mangal S. Yadav and Vinod K. Tiwari*

*Department of Chemistry, Centre of Advanced Study, Institute of Science, Banaras Hindu University, Varanasi, U.P. 221005, India, Email:

S. K. Singh, S. Kumar, M. S. Yadav, V. K. Tiwari, J. Org. Chem., 2022, 87, 15389-15402.

DOI: 10.1021/acs.joc.2c01951

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Complexes of pyridyl glycosyl triazoles with Cu(I) salts were explored as efficient catalysts to successfully assemble 2-amino-3-substituted and 3-substituted quinazolinones by domino/tandem cross-coupling reactions of various N-substituted o-halobenzamides with cyanamide and formamide, respectively.

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Key Words


ID: J42-Y2022