DBU-Catalyzed Aerobic CDC Reaction of Thiophenols
Xuemin Jia, Xiao Ma, Wei Feng, Ji-Quan Zhang, Yonglong Zhao, Bing Guo, Lei Tang* and Yuan-Yong Yang*
*School of Pharmacy, Guizhou Medical University, 550014 Guiyang, P. R. China,
Email: tlei1974
hotmail.com, yangyuanyonggmc.edu.cn
X. Jia, X. Ma, W.-F. J.-Q. Zhang, Y. Zhao, B. Guo, L. Tang, Y.-Y. Yang, J. Org. Chem., 2022, 87, 16492-16505.
DOI: 10.1021/acs.joc.2c02207
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Abstract
An environmentally friendly and operationally simple DBU-catalyzed aerobic cross-dehydrogenative coupling (CDC) reaction provides thiolated products of (hetero)aryl acetates, (hetero)aryl ketones, and indoles in good yields.
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proposed mechanism
Key Words
aryl sulfides, sulfides, oxygen
ID: J42-Y2022
