Zinc-Catalyzed Markovnikov-Type Hydroisothiocyanation of Alkenes with Ammonium Thiocyanate
Nobukazu Taniguchi*
*Department of Chemistry, Faculty of Liberal Arts, Sciences and Global Education, Osaka Metropolitan University, Sakai, Osaka 599-8531, Japan, Email: ntaniguchiomu.ac.jp
N. Taniguchi, Synlett, 2023, 34, 73-76.
DOI: 10.1055/a-1948-6798
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Abstract
A ZnI2-catalyzed addition of ammonium thiocyanate to olefins in the presence of 4-toluenesulfonic acid and tetrabutylammonium iodide proceeds by a Markovnikov-type process and a radical isomerization to provide the corresponding isothiocyanates selectively and in good yields.
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Key Words
zinc catalysis, Markovnikov reaction, isothiocyanates, thiocyanates, alkenes, isomerization
ID: J72-Y2023