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Recyclable Palladium-Catalyzed Carbonylative Cyclization of Aryl Iodides and 2-Hydroxyacetophenones towards Flavones

Gang Xie, Jianan Zhan, Mingzhong Cai*, Bin Huang*

*College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P. R. of China, Email: mzcaijxnu.edu.cn, huangb260163.com

G. Xie, J. Zhang, M. Cai, B. Huang, Synthesis, 2023, 55, 647-656.

DOI: 10.1055/s-0042-1753042


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Abstract

A MCM-41-immobilized bidentate phosphine palladium complex catalyzes an efficient carbonylative cyclization of aryl iodides and 2-hydroxyacetophenones under 3 bar of carbon monoxide in the presence of DBU in DMSO at 120C to provide a wide variety of flavones in very good yields. The supported palladium catalyst can be easily recovered via centrifugation and recycled more than nine times.


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Recyclable Heterogeneous Palladium-Catalyzed Carbonylative Cyclization of 2-Iodoanilines with Aryl Iodides Leading to 2-Arylbenzoxazinones

Z. Xu, B. Huang, Z. Zhou, M. Cai, Synthesis, 2020, 52, 581-590.


Key Words

palladium, carbonylative cyclization, flavones, aryl iodides, heterogeneous catalysis, multicomponent reactions


ID: J66-Y2023