Design, Synthesis, and Applications of a Vanadium Complex: An Effective Catalyst for the Direct Conversion of Alcohols and Aldehydes to Esters

Ghanshyam Mali, Indresh Verma, Himanshu Arora, Amit Rajput, Akhilesh Kumar* and Rohan D. Erande*

*Indian Institute of Technology Kanpur, Kanpur 208016; Indian Institute of Technology Jodhpur, Jodhpur 342037, Rajasthan, India, Email: akhileshiitk2012gmail.com, rd.erandeiitj.ac.in

G. Mali, I. Verma, H. Arora, A. Rajput, A. Kumar, R. D. Erande, J. Org. Chem., 2023, 88, 5696-5703.

DOI: 10.1021/acs.joc.3c00159

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Abstract

Aromatic aldehydes and benzylic alcohols are rapidly converted into esters derived from methanol, ethanol, iso-propanol, n-butanol, sec-butyl alcohol, and propargylic alcohol without additives in a one-pot manner using a bench-stable V-catalyst and H₂O₂ as a green oxidant. The developed method is compatible with a broad range of functional groups.

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proposed mechanism

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Key Words

oxidative esterification, hydrogen peroxide, vanadium

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ID: J42-Y2023