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Redox-Neutral Synthesis of Sulfilimines through the S-Alkylation of Sulfenamides

Guoling Huang, Xunbo Lu*, Kaiyuan Yang and Xinyu Xu

*Laboratory of Marine Green Fine Chemicals, School of Chemistry and Chemical Engineering, Lingnan Normal University, 29 Cunjin Road, Zhanjiang 524048, P. R. China, Email:

G. Huang, X. Lu, K. Yang, X. Xu, Org. Lett., 2023, 25, 3173-3178.

DOI: 10.1021/acs.orglett.3c01060

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A metal-free, sustainable, and efficient sulfur-selective alkylation of readily accessible sulfenamides with commercially available halogenated hydrocarbons under basic conditions provides sulfilimines in high yields and short reaction times.

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Redox-Neutral Strategy for Sulfilimines Synthesis via S-Arylation of Sulfenamides

G. Huang, X. Lu, F. Liang, Org. Lett., 2023, 25, 3179-3183.

Key Words


ID: J54-Y2023